2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone
2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone
CAS: 1111638-52-8
Molecular Formula: C20H16N4O3S2
2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone - Names and Identifiers
2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone - Physico-chemical Properties
| Molecular Formula | C20H16N4O3S2 |
| Molar Mass | 424.5 |
| Density | 1.43 |
| Boling Point | 673.8±65.0 °C(Predicted) |
| pKa | 0.49±0.20(Predicted) |
2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone - Introduction
2-[2-(Methylthio) pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo [2,3-b] pyridin-5-yl] ethanone is an organic compound commonly referred to as MTPTK. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid or light yellow powder.
-Molecular formula: C17H12N4O3S2
-Molecular weight: 396.43g/mol
-Melting point: 170-172°C
-Solubility: MTPTK is soluble in organic solvents such as alcohols, ethers and ketones, but hardly soluble in water.
Use:
As a sulfur-containing heterocyclic compound, MTPTK has many applications in organic synthesis:
-As an intermediate: MTPTK can be used as an intermediate for the synthesis of other organic compounds, such as pyrimidine derivatives.
-Fluorescent dyes: MTPTK can be used to prepare fluorescent dyes, such as cell imaging and fluorescent probes.
-Organic synthesis catalyst: MTPTK can be used as a catalyst for organic synthesis reactions to promote chemical reactions.
Preparation Method:
The preparation method of MTPTK can be achieved through organic synthesis routes. The following is a possible preparation method:
In a reactor, 2-methylthiopyrimidin-4-one and 1-(phenylsulfonyl)-2,3-dichloropyrrolo [2,3-b] pyridin -5-one are added to an appropriate solvent, and reacted with heating and stirring to generate MTPTK.
Safety Information:
- MTPTK may be toxic and irritant, and may have a certain impact on the environment. Appropriate safety measures, such as wearing protective gloves, glasses and protective clothing, are required for use. Ensure that the operation is carried out in a well-ventilated area, avoiding inhalation and contact with skin. In case of contact or ingestion, wash or seek medical attention immediately.
Nature:
-Appearance: White crystalline solid or light yellow powder.
-Molecular formula: C17H12N4O3S2
-Molecular weight: 396.43g/mol
-Melting point: 170-172°C
-Solubility: MTPTK is soluble in organic solvents such as alcohols, ethers and ketones, but hardly soluble in water.
Use:
As a sulfur-containing heterocyclic compound, MTPTK has many applications in organic synthesis:
-As an intermediate: MTPTK can be used as an intermediate for the synthesis of other organic compounds, such as pyrimidine derivatives.
-Fluorescent dyes: MTPTK can be used to prepare fluorescent dyes, such as cell imaging and fluorescent probes.
-Organic synthesis catalyst: MTPTK can be used as a catalyst for organic synthesis reactions to promote chemical reactions.
Preparation Method:
The preparation method of MTPTK can be achieved through organic synthesis routes. The following is a possible preparation method:
In a reactor, 2-methylthiopyrimidin-4-one and 1-(phenylsulfonyl)-2,3-dichloropyrrolo [2,3-b] pyridin -5-one are added to an appropriate solvent, and reacted with heating and stirring to generate MTPTK.
Safety Information:
- MTPTK may be toxic and irritant, and may have a certain impact on the environment. Appropriate safety measures, such as wearing protective gloves, glasses and protective clothing, are required for use. Ensure that the operation is carried out in a well-ventilated area, avoiding inhalation and contact with skin. In case of contact or ingestion, wash or seek medical attention immediately.
Last Update：2024-04-10 22:29:15
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